Would the name [name_f]Jane[/name_f] [name_f]Kathleen[/name_f] [name_u]Jean[/name_u] be okay, or is it too weird since they all end in an N and [name_f]Jane[/name_f] and [name_u]Jean[/name_u] are anagrams? All of these names have a special meaning and we would hate to not use one of them.
I think it’s fine. I love [name_f]Jane[/name_f] and [name_f]Kathleen[/name_f].
Since they are all meaningful I think you should use them all. Most people won’t even know her middle names and that’s why I consider significance the most important thing. So long as the names don’t sound ridiculous together, which these do not.
For me it would seem odd, not for the reasons you have given, but because [name_f]Jane[/name_f] and [name_u]Jean[/name_u] are the same name essentially. [name_u]Jean[/name_u] is the Scottish form of [name_f]Jane[/name_f], and is sometimes pronounced as [name_f]Jane[/name_f]. In my Scottish family history, for some relatives, [name_f]Jane[/name_f] and [name_u]Jean[/name_u] are interchangeable forms for the same person.
I agree with araminty. [name_f]Jane[/name_f] and [name_u]Jean[/name_u] are basically different versions of the same name, so I would find it very odd to see them used in the same combination. It would be like [name_f]Isabel[/name_f] [name_f]Elizabeth[/name_f] or [name_f]Mary[/name_f] [name_f]Maria[/name_f] or [name_f]Megan[/name_f] [name_f]Margaret[/name_f]. If [name_f]Jane[/name_f] and [name_u]Jean[/name_u] are honor names for two different people, I would just pick the one you like best and say it’s in honor of both of them.