My husband and I have been searching for a name we loved as much as [name]Wesley[/name] and I think we found it. What do you think of [name]Wesley[/name] and [name]Jacob[/name]? 
I like both names and they do sound good together: they both have history and are clearly boys’ names, so they work. It’s also important that you love both names, so that box is checked and you’re off to a good start. It should absolutely be a strong contendor for the combo. If you’re done looking, you’re done, and you’ve done well.
BUT if you’re still looking / want more detail, I do have some mild pause about popularity and image. [name]Jacob[/name] is literally the #1 boys name in the country and has a very strong sound. [name]Wesley[/name] is at 156 and has a more sensitive sound. If you’re open to others, [name]James[/name] and [name]Wesley[/name] or [name]Caleb[/name] and [name]Wesley[/name] are combos with a lot of overlap with [name]Jacob[/name] and [name]Wesley[/name] that to me are a bit more closely matched in popularity and sound. [name]Just[/name] options and opinion though. Good luck whatever you decide!
I really like [name]Jacob[/name] and [name]Wesley[/name] as twins! [name]Jake[/name] and [name]Wes[/name] could so easily be two handsome cowboys. 
I completely agree with jesba. I think it’s a good choice, and if you love it, you should go for it! When I saw the title of your thread, I immediately thought [name]Nelson[/name] would make a great twin for [name]Wesley[/name]! [name]Just[/name] a thought.
[name]Love[/name] the twinset of [name]Jacob[/name] and [name]Wesley[/name].
As long as you don’t go for [name]John[/name] and [name]Wesley[/name], you’re fine!! 